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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYP4A22
All Species:
23.94
Human Site:
Y120
Identified Species:
65.83
UniProt:
Q5TCH4
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5TCH4
NP_001010969.2
519
59246
Y120
D
P
K
S
H
G
S
Y
K
F
L
A
P
R
I
Chimpanzee
Pan troglodytes
XP_513388
519
59324
Y120
D
P
K
S
H
G
S
Y
R
F
L
A
P
W
I
Rhesus Macaque
Macaca mulatta
XP_001109135
519
59279
Y120
D
P
K
S
Q
D
P
Y
R
F
L
A
P
W
I
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O88833
509
58321
Y119
D
P
K
A
N
G
A
Y
R
L
L
A
P
W
I
Rat
Rattus norvegicus
P08516
509
58197
Y119
D
P
K
A
N
G
V
Y
R
L
L
A
P
W
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520882
506
58357
Y114
D
P
K
N
K
A
A
Y
R
F
A
V
P
W
I
Chicken
Gallus gallus
XP_422455
504
57538
Y117
D
P
K
P
P
V
P
Y
Q
F
L
V
P
W
I
Frog
Xenopus laevis
NP_001091126
516
59853
Y117
D
P
K
D
E
T
A
Y
K
Y
I
V
P
W
I
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VXY0
495
57171
R124
G
E
S
W
H
R
R
R
K
L
L
T
P
G
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98
92
N.A.
N.A.
73.4
73.4
N.A.
55.2
54.3
54.7
N.A.
N.A.
35
N.A.
N.A.
N.A.
Protein Similarity:
100
98.4
94.8
N.A.
N.A.
83.6
83.6
N.A.
69.3
70.5
70.7
N.A.
N.A.
53.5
N.A.
N.A.
N.A.
P-Site Identity:
100
86.6
66.6
N.A.
N.A.
60
60
N.A.
46.6
53.3
46.6
N.A.
N.A.
26.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
73.3
N.A.
N.A.
86.6
80
N.A.
66.6
60
66.6
N.A.
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
23
0
12
34
0
0
0
12
56
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
89
0
0
12
0
12
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
12
0
0
12
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
56
0
0
0
0
12
% F
% Gly:
12
0
0
0
0
45
0
0
0
0
0
0
0
12
0
% G
% His:
0
0
0
0
34
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
89
% I
% Lys:
0
0
89
0
12
0
0
0
34
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
34
78
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
12
23
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
89
0
12
12
0
23
0
0
0
0
0
100
0
0
% P
% Gln:
0
0
0
0
12
0
0
0
12
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
12
12
12
56
0
0
0
0
12
0
% R
% Ser:
0
0
12
34
0
0
23
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
12
0
0
0
0
0
12
0
0
0
% T
% Val:
0
0
0
0
0
12
12
0
0
0
0
34
0
0
0
% V
% Trp:
0
0
0
12
0
0
0
0
0
0
0
0
0
78
0
% W
% Tyr:
0
0
0
0
0
0
0
89
0
12
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _